ANTENATAL DIAGNOSIS OF SICKLE-CELL ANÆMIA BY D.N.A. ANALYSIS OF AMNIOTIC-FLUID CELLS

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Chromatin, Dna Sequencing, Dna +15

Midtrimester Amniocentesis for Prenatal Diagnosis

Abraham A. Ghiatas · JAMA · 1976 · 389 citations

Midtrimester Amniocentesis, Fertility, Fetal Medicine +13

Application of Endonuclease Mapping to the Analysis and Prenatal Diagnosis of Thalassemias Caused by Globin-Gene Deletion

Stuart H. Orkin, Blanche P. Alter, Çiğdem Altay et al. · New England Journal of Medicine · 1978 · 208 citations

Identification of a Nondeletion Defect in α-Thalassemia

Yuet Wai Kan, Andrée M. Dozy, Richard F. Trecartin et al. · New England Journal of Medicine · 1977 · 193 citations

Anemia, Molecular Defect, Chinese Family +11

Prenatal Diagnosis of α-Thalassemia

Yuet Wai Kan, Mitchell S. Golbus, Andrée M. Dozy · New England Journal of Medicine · 1976 · 145 citations

Infertility, Fertility, Genetics +13