Chemical Communications · 2007 · 53 citations · 46 references
EngineeringMolecular BiologyGene DeliveryNovel Amino-functionalised MulticalixarenesGenome EngineeringAntisense TherapyAliphatic AminesGene TransferBioconjugationOligonucleotideEfficient Gene TransfectionPharmacologyCell EngineeringBiomolecular EngineeringEffective Dna BindingSynthetic BiologyGenetic EngineeringGene VectorMedicineGenome EditingDrug Discovery
Novel amino-functionalised multicalixarenes have been synthesised which show low cellular toxicity, effective DNA binding and, when featuring aliphatic amines, are efficient gene transfection agents.
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