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Cooperative N-methyl-d-aspartate (NMDA) receptor antagonism and μ-opioid receptor agonism mediate the methadone inhibition of the spinal neuron pain-related hyperactivity in a rat model of neuropathic pain

Pain TherapyPain DisordersPain MedicineNeuropathic PainMolecular PainReceptor AntagonismRat ModelMolecular PharmacologyPain ManagementAnalgesicsHealth SciencesNeuropharmacologyPharmacologyPain ResearchMethadone InhibitionAddictionNeurosciencePain MechanismMedicine