Importance of IgG2c isotype in the immune response to β-amyloid in amyloid precursor protein/transgenic mice

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

Life Sciences, Neurobiology, Neuroscience +17

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.2K citations

Life Sciences, Neurology, Neuroscience +14

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

Life Sciences, Neurology, Neuroscience +16

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard, Catherine Cannon, Robin Barbour et al. · Nature Medicine · 2000 · 2K citations

Life Sciences, Neurology, Neuroscience +17

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

Christine Stürchler-Pierrat, Dorothée Abramowski, Mairead Duke et al. · Proceedings of the National Academy of Sciences · 1997 · 1.5K citations · Full text

Life Sciences, Neuroscience, Pathology +17