Eosinophilic Granuloma

Abstract

EOSINOPHILIC granuloma is a rare disease of bone that has only recently been described as an entity. Approximately 45 cases have been reported in the literature. The condition was simultaneously described in 1940 by Lichtenstein and Jaffe1 and by Otani and Ehrlich.2 The former employed the term "eosinophilic granuloma," and the latter "solitary granuloma of bone," to describe the same pathologic process. Otani and Ehrlich's term has largely been dropped, because the lesions are not always solitary and "eosinophilic granuloma" gives a connotation that adds specificity to the mental picture of the lesion. Two previous reports3 , 4 in the literature described . . .