Unraveling Overlapping Multiplets in Two‐Dimensional NMR Correlation Spectra by Selective Inversion of Coupling Partners

Abstract

Clean and simple two‐dimensional multiplet pallerns instead of overlapping multiplets can be generated in an NMR experiment by employing selective pulses that single out small segments of a complete spectrum. The pattern of the selected multiplet is in this case manipulated by altering the apparent signs of the coupling constants. The technique is suitable not only for separating overlapping signals, but also for testing hypotheses associated with particular coupling networks.