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A Seven‐Day variability study of 499 patients with peripheral rheumatoid arthritis
240
Citations
5
References
1965
Year
Rheumatoid DisorderClinical EpidemiologyClinical TrialsChronic Musculoskeletal ConditionInflammatory Rheumatic DiseaseDrug MonitoringDisease AssessmentLaboratory MedicineClinical EvaluationRheumatoid ArthritisHealth SciencesPhysical MedicineRheumatologyTherapeutic Drug MonitoringAutoimmune DiseaseRheumatic DiseasesOutcomes ResearchPhysical TherapyPeripheral Rheumatoid ArthritisMorning StiffnessPatient SafetySeven‐day Variability StudyDisease ActivityClinical MeasurementMedicineInitial Disease Severity
Abstract At eleven clinics uniform methods of measuring disease activity (duration of morning stiffness, grip strength, number of active joints, erythrocyte sedimentation rate) produced two sets of tables: (1) interpatient single‐examination differences (499 patients); (2) changes in one week (411 patients with unchanged therapy). The second set of tables provides inter alia standards for screening new drugs and a method of correcting for initial disease severity in controlled trials.
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