Concepedia

The Granular Chloride Channel ClC-3 Is Permissive for Insulin Secretion

Ludmila V. Deriy, Erwin A. Gomez, David A. Jacobson, XueQing Wang, Jessika A. Hopson, Xiang Y. Liu, Guangping Zhang, Vytautas P. Bindokas, Louis H. Philipson, Deborah J. Nelson

Cell Metabolism · 2009 · 70 citations · 34 references

DOIFull text

Open access

Concepts

References

34

Disruption of ClC-3, a Chloride Channel Expressed on Synaptic Vesicles, Leads to a Loss of the Hippocampus

Sandra M. Stobrawa, Tilman Breiderhoff, Shigeo Takamori et al. · Neuron · 2001 · 509 citations · Full text

, , +14

Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles.

Lelio Orci, Mariella Ravazzola, M Amherdt et al. · The Journal of Cell Biology · 1986 · 335 citations · Full text

, , +14

Transgenic mice with green fluorescent protein-labeled pancreatic β-cells

Manami Hara, Xiaoyu Wang, Toshihiko Kawamura et al. · American Journal of Physiology-Endocrinology and Metabolism · 2003 · 301 citations

, , +16

Exocytosis elicited by action potentials and voltage‐clamp calcium currents in individual mouse pancreatic B‐cells.

Carina Ämmälä, Lena Eliasson, Krister Bokvist et al. · The Journal of Physiology · 1993 · 274 citations

, , +17

Priming of insulin granules for exocytosis by granular Cl− uptake and acidification

Sebastian Barg, Ping Huang, Lena Eliasson et al. · Journal of Cell Science · 2001 · 198 citations

, , +17