Effects of time and 8-azaguanine on the development of morphine tolerance

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

Public Health, Biostatistics, Pharmacology +12

THE EVALUATION OF THE ANALGESIC ACTION OF PETHIDINE HYDROCHLORIDE (DEMEROL)

G. Woolfe, Alex MacDonald · Journal of Pharmacology and Experimental Therapeutics · 1944 · 1K citations

Medicine, Medicinal Chemistry, Pharmacology +13

A General Theory of the Genesis of Drug Dependence by Induction of Receptors

H. O. J. COLLIER · Nature · 1965 · 149 citations

Medicine, Pharmacology, General Pharmacology +13

TOLERANCE TO MORPHINE. I. EFFECTS ON CATECHOLAMINES IN THE BRAIN AND ADRENAL GLANDS

E.W. Maynert, Gerda I. Klingman · Journal of Pharmacology and Experimental Therapeutics · 1962 · 144 citations

Medicine, Neuroscience, Pharmacology +17

Catecholamines and 5-hydroxytryptamine in morphine tolerance and withdrawal.

Lars M. Gunne · PubMed · 1963 · 120 citations

Medicine, Pharmacology, Pharmacotherapy +12