A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production

Xiaoqiang Chen, Kyung‐Ah Lee, Eun-Mi Ha, Kyung‐Mi Lee, You Yeong Seo, Han Kyoung Choi, Ha Na Kim, Min Jung Kim, Chun‐Seok Cho, Soo Young Lee,

Chemical Communications · 2011 · 245 citations · 32 references

Concepts

Abstract

A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.

References

32