1,3-Carbon D–A strategy for [3 + 2] cycloadditions/annulations with imines: synthesis of functionalized pyrrolidines and related alkaloids

Abstract

[3 + 2] Cycloaddition/annulation: this article summarize the recent developments in synthesis of pyrrolidines and related alkaloids through complementary [3 + 2] cycloaddition/annulation of 1,3-carbon D–A precursors with imines.