Performance of pectolytic enzymes during hydrolysis of pectic substances under assay conditions: a statistical approach

On the Experimental Attainment of Optimum Conditions

George E. P. Box, Kerry Wilson · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1951 · 4.4K citations

Public Health, Mathematics, Experimental Design +4

An Automatic Method for Finding the Greatest or Least Value of a Function

H.H. Rosenbrock · The Computer Journal · 1960 · 2.9K citations

Computing, Computer Science, Mathematics +5

Response Surfaces: Designs and Analyses

Eric R. Ziegel, André I. Khuri, John A. Cornell · Technometrics · 1997 · 1.5K citations

Public Health, Design, Experimental Design +4

Multi-Factor Experimental Designs for Exploring Response Surfaces

George E. P. Box, J. Stuart Hunter · The Annals of Mathematical Statistics · 1957 · 1.4K citations · Full text

Public Health, Biostatistics, Design Optimization +7

Substrate reactivity as a function of the extent of reaction in the enzymatic hydrolysis of lignocellulose

Sunil G. Desai, Alvin O. Converse · Biotechnology and Bioengineering · 1997 · 88 citations

Life Sciences, Biochemistry, Biotechnology +17