Asymmetric Synthesis of Highly Substituted γ-Amino Acids from Allyltitanium Sulfoximines

Abstract

[structure: see text]. Asymmetric syntheses of the highly substituted protected gamma-amino acids 10a, 10b, 18, and 21 have been developed starting from the allyltitanium sulfoximines V and VI, respectively, and furan-2-carbaldehyde.