C₉ Helices and Ribbons in γ‐Peptides: Crystal Structures of Gabapentin Oligomers

Abstract

Nine is the number: Novel C9-hydrogen-bonded structures (in which the hydrogen bonds enclose a ring of nine atoms) are observed in protected di- and tetrapeptides formed by the γ-amino acid residue gabapentin. The structures reveal new families of C9 helices and ribbons (see structure) in γ-polypeptides.