Characterization of the muscarinic receptor subtypes in the rat urinary bladder

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Pirenzepine distinguishes between different subclasses of muscarinic receptors

Rudolf Hammer, Christopher P. Berrie, N.J.M. Birdsall et al. · Nature · 1980 · 1.3K citations

Medicine, Neuroscience, Pharmacology +16

Muscarinic receptor subtypes: M1 and M2 biochemical and functional characterization

Rudolf Hammer, Antonio Giachetti · Life Sciences · 1982 · 697 citations

Medicine, Neuroscience, Pharmacology +14

Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat

Rudolf Hammer, E. Giraldo, G.B. Schiavi et al. · Life Sciences · 1986 · 370 citations

Medicine, Neuroscience, Pharmacology +15

A COMPARISON OF AFFINITY CONSTANTS FOR MUSCARINE‐SENSITIVE ACETYLCHOLINE RECEPTORS IN GUINEA‐PIG ATRIAL PACEMAKER CELLS AT 29°C AND IN ILEUM AT 29°C AND 37°C

R. B. BARLOW, K.J. BERRY, Patricia A. Glenton et al. · British Journal of Pharmacology · 1976 · 292 citations · Full text

Medicine, Biochemistry, Pharmacology +16