Concepedia

Effect of the CYP3A inhibitor ketoconazole on the pharmacokinetics and pharmacodynamics of bortezomib in patients with advanced solid tumors: A prospective, multicenter, open-label, randomized, two-way crossover drug—drug interaction study

Karthik Venkatakrishnan, Michael Rader, Ramesh K. Ramanathan, Suresh S. Ramalingam, Eric X. Chen, William Riordan, William L. Trepicchio, Michael R. Cooper, Michael D. Karol, Lisa Von Moltke,

Clinical Therapeutics · 2009 · 62 citations · 43 references

DOI

Concepts

References

43

The clinical evaluation of chemotherapeutic agents in cancer

David A. Karnofsky · Medical Entomology and Zoology · 1949 · 2.9K citations

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A Phase 2 Study of Bortezomib in Relapsed, Refractory Myeloma

Paul G. Richardson, Bart Barlogie, James R. Berenson et al. · New England Journal of Medicine · 2003 · 2.6K citations · Full text

, , +10

Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma

Paul G. Richardson, Pieter Sonneveld, Michael W. Schuster et al. · New England Journal of Medicine · 2005 · 2.5K citations · Full text

, , +14

Clinical pharmacokinetics; concepts and applications

General Pharmacology The Vascular System · 1989 · 2.2K citations

, , +12

Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma

Jesús F. San Miguel, Rudolf Schlag, Nuriet K. Khuageva et al. · New England Journal of Medicine · 2008 · 1.9K citations · Full text

, , +12