Effect of DDT or Parathion on Audiogenic Seizures of Offspring from Ddt- or Parathion-Treated Mothers

Abstract

DDT, Parathion, or corn oil (control) was administered to gravid mice during the first, second, and third trimesters of pregnancy. Incidence of audiogenic seizure was used to study the effect of the insecticides in the offspring. These compounds affected the maturation of the nervous system regardless of the stage of pregnancy during which they were administered. The high incidence of seizures in all of the groups of offspring had passed by 28 days of age. The insecticides did not influence the percentage of incidence after 20 days of age.