Mechanism of activation of protein kinase B by insulin and IGF-1.

Dario R. Alessi, Mirjana Andjelković, B. Caudwell, +4

The EMBO Journal

Molecular PhysiologySignal TransductionSignaling PathwayGrowth HormoneDiabetes +7

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

Hidenori Ichijo, Eisuke Nishida, Kenji Irie, +7

Science

Mammalian Ras interacts directly with the serine/threonine kinase raf

Anne B. Vojtek, Stanley M. Hollenberg, Jonathan A. Cooper

Cell

Signal TransductionMolecular PhysiologySerine/threonine Kinase RafSignaling PathwayCell Regulation +4

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

Masahiko Hibi, Anning Lin, Tod Smeal, +2

Genes & Development

Molecular RegulationMolecular BiologySerines 63Cellular PhysiologyUv Light +16

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

Michael B. Yaffe, Katrin Rittinger, Stefano Volinia, +6

Cell

BiochemistryNatural SciencesPeptide LibraryMolecular BiologyProtein Phosphorylation +4

Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms

Benoît Dérijard, Joël Raingeaud, Tamera Barrett, +4

Science

Systems BiologyMolecular PhysiologySignal TransductionP38 Map KinaseCell Regulation +12

Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine

Anthony J. Muslin, J. William Tanner, Paul M. Allen, +1

Cell

Proteins IsSignal TransductionSignaling PathwayBiochemistryMolecular Pathway +7

MKK3- and MKK6-Regulated Gene Expression Is Mediated by the p38 Mitogen-Activated Protein Kinase Signal Transduction Pathway

Joël Raingeaud, Alan J. Whitmarsh, Tamera Barrett, +2

Molecular and Cellular Biology

Signal TransductionP38 Map KinaseCell RegulationMolecular PathwayReceptor Tyrosine Kinase +10

The "megaprimer" method of site-directed mutagenesis.

Gobinda Sarkar, S S Sommer

PubMed

EngineeringGeneticsOligonucleotide PrimersMolecular BiologyMolecular Genetics +16

Phosphorylation and Regulation of Raf by Akt (Protein Kinase B)

Sven Zimmermann, Karin Moelling

Science

Cell DeathCancer BiologyTumor BiologySignaling PathwayCell Regulation +19