Studies on Granuloma Inguinale. V. Isolation of Bacterium resembling Donovania granulomatis from the Faeces of a Patient with Granuloma Inguinale.

Abstract

Anderson (1943), and later Anderson, DeMon- breun, and Goodpasture (1945) were able to isolate a bacterium from the lesions of three cases of granuloma inguinale. These authors were able to show that this bacterium, provisionally named Donovania granulomatis, morphologically resembles the Donovan body and that, when prepared as antigen, it reacts with sera from cases of granuloma inguinale. The bacterium has unusual nutritional requirements, requiring egg-yolk material for growth and does not grow on any of the enriched media used to grow fastidious bacteria. These unusual requirements are strong evidence that this bacterium is not similar to any of the various bacteria previously isolated from granuloma inguinale.