Transmyocardial Laser Revascularization Combined with Intramyocardial Endothelial Progenitor Cell Transplantation in Patients with Intractable Ischemic Heart Disease Ineligible for Conventional Revascularization: Preliminary Results in a Highly Selected Small Patient Cohort - Concepedia

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Transmyocardial Laser Revascularization Combined with Intramyocardial Endothelial Progenitor Cell Transplantation in Patients with Intractable Ischemic Heart Disease Ineligible for Conventional Revascularization: Preliminary Results in a Highly Selected Small Patient Cohort

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References

2010

Year

Jörg Babin–Ebell, Hans‐Hinrich Sievers, Efstratios I. Charitos, Hans-Martin Klein, F. Jung, A.-K. Hellberg, Reinhard Depping, HA Sier, Jan H. Marxsen, Stephanie Stoelting,

The Thoracic and Cardiovascular Surgeon

Abstract

In this small patient cohort, intramyocardial CD 133+ cell injection combined with transmyocardial laser revascularization led to an improvement in clinical symptomatology in all patients and in left ventricular function in 4 out of 5 patients, with an unclear effect on myocardial perfusion. Caution is advised when employing this therapy in patients with severely depressed left ventricular function.