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Novel tetrahydro-β-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

John I. Trujillo, Marvin J. Meyers, David R. Anderson, Shridhar G. Hegde, Matthew Mahoney, William F. Vernier, Ingrid P. Buchler, Kun Wu, Syaluan Yang, Susan J. Hartmann,

Bioorganic & Medicinal Chemistry Letters · 2007 · 137 citations · 12 references

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12

MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis

Alexey Kotlyarov, Armin Neininger, Carola Schubert et al. · Nature Cell Biology · 1999 · 767 citations

, , +14

MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels

Armin Neininger, Dimitris L. Kontoyiannis, Alexey Kotlyarov et al. · Journal of Biological Chemistry · 2002 · 389 citations · Full text

, , +17

Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

David R. Anderson, Shridhar G. Hegde, Emily J. Reinhard et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 265 citations · Full text

, , +10

Eudistomins A-Q, .beta.-carbolines from the antiviral Caribbean tunicate Eudistoma olivaceum

Kenneth L. Rinehart, Jun’ichi Kobayashi, Gary C. Harbour et al. · Journal of the American Chemical Society · 1987 · 239 citations

, , +9

Pyrrolopyridine Inhibitors of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK-2)

David R. Anderson, Marvin J. Meyers, William F. Vernier et al. · Journal of Medicinal Chemistry · 2007 · 170 citations · Full text

, , +17