Evaluation of Cannabimimetic Discriminative Stimulus Effects of Anandamide and Methylated Fluoroanandamide in Rhesus Monkeys

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, L Hanŭs, Aviva Breuer et al. · Science · 1992 · 5.6K citations

Brain Constituent, Neurotransmitter, Cannabinoid Pharmacology +17

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

Vincenzo Di Marzo, Angelo Fontana, Hugues Cadas et al. · Nature · 1994 · 1.6K citations

Cannabis Use, Psychoactive Drug, Molecular Neuroscience +11

Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist

Dale G. Deutsch, Suzette A. Chin · Biochemical Pharmacology · 1993 · 700 citations

Cannabis Use, Biochemistry, Functional Selectivity +4

Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.

Christian C. Felder, Eileen M. Briley, J Axelrod et al. · Proceedings of the National Academy of Sciences · 1993 · 474 citations · Full text

Human Cannabinoid Receptor, Endogenous Cannabimimetic Eicosanoid, Synthetic Anandamide +18

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.

David M. Compton, Kenner C. Rice, Barbara Costa et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 462 citations · Full text