Presence of somatomedin receptors on primary human breast and colon carcinomas

Insulin‐like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

A. Ullrich, Andrew Gray, Albert W. Tam et al. · The EMBO Journal · 1986 · 1.9K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Autocrine Secretion and Malignant Transformation of Cells

Michael B. Sporn, George J. Todaro · New England Journal of Medicine · 1980 · 1.4K citations

Life Sciences, Cancer Biology, Cell Biology +17

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor.

Joan Massagué, Michael Czech · Journal of Biological Chemistry · 1982 · 714 citations · Full text

Life Sciences, Biochemistry, Endocrinology +16

Cellular Localization of Somatomedin (Insulin-Like Growth Factor) Messenger RNA in the Human Fetus

Victor K. M. Han, A. Joseph D’Ercole, P. Kay Lund · Science · 1987 · 662 citations

Life Sciences, Developmental Biology, Molecular Biology +12

Insulin‐Like Growth Factors I and II: Some Biological Actions and Receptor Binding Characteristics of Two Purified Constituents of Nonsuppressible Insulin‐Like Activity of Human Serum

Jürgen Zapf, Eugen J. Schoenle, E. R. Froesch · European Journal of Biochemistry · 1978 · 380 citations · Full text

Life Sciences, Biochemistry, Endocrinology +15