Morphine tolerance in arthritic rats and serotonergic system

Ethical guidelines for investigations of experimental pain in conscious animals

M. Zimmermann · Pain · 1983 · 7.8K citations

Medicine, Anesthesiology, Animal Sciences +14

The nature of opioid responsiveness and its implications for neuropathic pain: new hypotheses derived from studies of opioid infusions

Russell K. Portenoy, Kathleen M. Foley, Charles E. Inturrisi · Pain · 1990 · 566 citations

Medicine, Pharmacokinetics, Pharmacology +15

Experimental mononeuropathy reduces the antinociceptive effects of morphine: implications for common intracellular mechanisms involved in morphine tolerance and neuropathic pain

Jianren Mao, Donald D. Price, David J. Mayer · Pain · 1995 · 329 citations

Medicine, Neuroscience, Pharmacology +17

The effect of spinal GABA receptor agonists on tactile allodynia in a surgically-induced neuropathic pain model in the rat

Jai Hyun Hwang, Tony L. Yaksh · Pain · 1997 · 249 citations

Medicine, Neurobiology, Pharmacology +17

A new method for the evaluation of analgesic activity using adjuvant-induced arthritis in the rat

Anthony W. Pircio, Cosmo T. Fedele, M. E. Bierwagen · European Journal of Pharmacology · 1975 · 150 citations

Medicine, Pharmacology, Pain Medicine +8