Inhibition of MMTV transcription by HDAC inhibitors occurs independent of changes in chromatin remodeling and increased histone acetylation

The language of covalent histone modifications

Brian D. Strahl, C. David Allis · Nature · 2000 · 8.6K citations

Life Sciences, Biochemistry, Molecular Biology +12

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Manfred Gossen, Heidelberg Bujard · Proceedings of the National Academy of Sciences · 1992 · 5K citations

Life Sciences, Genetics, Molecular Biology +17

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

Vasily Ogryzko, R. Louis Schiltz, Valya Russanova et al. · Cell · 1996 · 3K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

V. G. Allfrey, Robert Faulkner, A. E. Mirsky · Proceedings of the National Academy of Sciences · 1964 · 2.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

James E. Brownell, Tamara A. Ranalli, Ryûji Kobayashi et al. · Cell · 1996 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +17