Concepedia

Phase I study of oral gemcitabine prodrug (LY2334737) in Japanese patients with advanced solid tumors

Noboru Yamamoto, Hiroshi Nokihara, Yasuhide Yamada, Kazunori Uenaka, Risa Sekiguchi, Takeshi Makiuchi, Christopher A. Slapak, Karim A. Benhadji, Tomohide Tamura

Cancer Chemotherapy and Pharmacology · 2013 · 17 citations · 20 references

DOI

Concepts

References

20

New Guidelines to Evaluate the Response to Treatment in Solid Tumors

Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer et al. · JNCI Journal of the National Cancer Institute · 2000 · 15.7K citations

, , +12

A phase I clinical, plasma, and cellular pharmacology study of gemcitabine.

James L. Abbruzzese, Ralf Grunewald, Elizabeth A. Weeks et al. · Journal of Clinical Oncology · 1991 · 759 citations

, , +13

Randomized Phase II Comparison of Dose-Intense Gemcitabine: Thirty-Minute Infusion and Fixed Dose Rate Infusion in Patients With Pancreatic Adenocarcinoma

Margaret A. Tempero, William Plunkett, Veronique Ruiz van Haperen et al. · Journal of Clinical Oncology · 2003 · 522 citations

, , +16

Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan.

Guang Xu, Wanghai Zhang, Howard L. McLeod · PubMed · 2002 · 278 citations

, , +12

Phase II Clinical Investigation of Gemcitabine in Advanced Soft Tissue Sarcomas and Window Evaluation of Dose Rate on Gemcitabine Triphosphate Accumulation

Shreyaskumar Patel, Varsha Gandhi, Jan Jenkins et al. · Journal of Clinical Oncology · 2001 · 246 citations

, , +17