Octanol-Water Partition Coefficients of Simple Organic Compounds

Abstract

Octanol-water partition coefficients (log P) for 611 simple organic compounds representing all principal classes have been retrieved from the literature. Available experimental details of measurement are documented from original articles. Pertinent thermodynamic relations are presented, with a discussion of direct and indirect methods of measurement. Reported log P data for each compound have been evaluated according to stated criteria, and recommended values (with uncertainty) are given.