Journal of Natural Products · 2003 · 39 citations · 6 references
Natural SciencesMarine BiologyMarine SciencesMarine ToxicologyMarine Bioactive CompoundsMarine Drug DiscoveryMarine Natural ProductsAnticancer Marine CompoundsBioactive Compounds From Marine SpongesCytotoxicity AssaysMarine Sponge MetabolitesMarine TerpenoidsMarine-derived Anticancer CompoundsSponges As Drug SourcesSponges-derived Metabolites
Three new sesterterpenes (1-3) were isolated from a marine sponge of the genus Spongia, and their structures were determined on the basis of spectroscopic analysis. The compounds 1-3 exhibited cytotoxicity against HeLa cells with IC(50) values of 19.5, 15.0, and 5.3 microg/mL, respectively.
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Ichthyotoxic sesterterpenoids from the neo guinean sponge carteriospongia foliascens
J.C. Baekman, D. Daloze, M. Kaisin et al. · Tetrahedron · 1985 · 42 citations