PASSflow Syntheses Using Functionalized Monolithic Polymer/Glass Composites in Flow-Through Microreactors Part of these studies were supported by the Fonds der Chemischen Industrie and the European Community (EC project number HPRI-CT-1999-00085) for which we are grateful. PASSflow=Polymer Assisted Solution-Phase Synthesis technique in flow-through mode.

Abstract

A chemistapos;s wish finally becomes reality: microreactors for every synthetic laboratory! By precipitation polymerization various polymers are introduced into the irregular pore system of a porous glass rod. By embedding these rods into a housing, followed by functionalization and immobilization of reagents onto the polymer phase, versatile microreactors are obtained. With this apparatus, chemical transformations in solution can be performed, for example, a steroid derivatization.