Concepedia

Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5

Xiaodong Sun, Xingjuan Shi, Xiaoou Sun, Youguang Luo, Xiaojing Wu, Changfu Yao, Haiyang Yu, Deng-wen Li, Min Liu, Jun Zhou

Acta Pharmacologica Sinica · 2011 · 49 citations · 20 references

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Cancer Statistics, 2009

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2009 · 9.7K citations · Full text

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Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5

Tarun M. Kapoor, Thomas U. Mayer, Margaret Coughlin et al. · The Journal of Cell Biology · 2000 · 731 citations · Full text

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The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

Lukas C. Kapitein, Erwin J.G. Peterman, Benjamin H. Kwok et al. · Nature · 2005 · 700 citations · Full text

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Establishment of a continuous tumor‐cell line (PANC‐1) from a human carcinoma of the exocrine pancreas

Michael M. Lieber, Joann Mazzetta, Walter A. Nelson‐Rees et al. · International Journal of Cancer · 1975 · 503 citations

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Myosin IIA regulates cell motility and actomyosin–microtubule crosstalk

Sharona Even‐Ram, Andrew D. Doyle, Mary Anne Conti et al. · Nature Cell Biology · 2007 · 503 citations

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