Boolean formalization of genetic control circuits

Genetic regulatory mechanisms in the synthesis of proteins

François Jacob, Jacques Monod · Journal of Molecular Biology · 1961 · 6.6K citations

Life Sciences, Genetics, Molecular Biology +12

Metabolic stability and epigenesis in randomly constructed genetic nets

Stuart Kauffman · Journal of Theoretical Biology · 1969 · 4.9K citations

Life Sciences, Biology, Systems Biology +10

INHIBITION BY GLUCOSE OF THE INDUCED SYNTHESIS OF THE β-GALACTOSIDE-ENZYME SYSTEM OF <i>ESCHERICHIA COLI</i> . ANALYSIS OF MAINTENANCE

Melvin Cohn, Kengo Horibata · Journal of Bacteriology · 1959 · 150 citations · Full text

Life Sciences, Biochemistry, Microbiology +13

ANALYSIS OF THE DIFFERENTIATION AND OF THE HETEROGENEITY WITHIN A POPULATION OF <i>ESCHERICHIA COLI</i> UNDERGOING INDUCED β-GALACTOSIDASE SYNTHESIS

Melvin Cohn, Kengo Horibata · Journal of Bacteriology · 1959 · 115 citations · Full text

Life Sciences, Genetics, Microbiology +11

Functional analysis of chemical systems in vivo using a logical circuit equivalent. II. The idea of a molecular automaton

Motoyosi Sugita · Journal of Theoretical Biology · 1963 · 112 citations

Natural Sciences, Biochemistry, Chemistry +10