Concepedia

MicroRNA-101a Inhibits Cardiac Fibrosis Induced by Hypoxia via Targeting TGFβRI on Cardiac Fibroblasts

Xin Zhao, Kejing Wang, Yuhua Liao, Qiutang Zeng, Yushu Li, Fen Hu, Yuzhou Liu, Kai Meng, Cheng Qian, Qing Zhang,

Cellular Physiology and Biochemistry · 2015 · 111 citations · 26 references

Open access

Abstract

Our study illustrates that miR-101a exerts anti-fibrotic effects by targeting TGFβRI, suggesting that miR-101a plays a multi-faceted role in modulating TGF-β signaling pathway and cardiac fibrosis.

References

26

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

Eva van Rooij, Lillian B. Sutherland, Jeffrey E. Thatcher et al. · Proceedings of the National Academy of Sciences · 2008 · 1.8K citations · Full text

Heart Failure, Immunology, Pathology +16

MicroRNA-133 controls cardiac hypertrophy

Alessandra Carè, Daniele Catalucci, Federica Felicetti et al. · Nature Medicine · 2007 · 1.8K citations

Cardiomyopathy, Cardiovascular Disease, Physiology +5

Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA

Eva van Rooij, Lillian B. Sutherland, Xiaoxia Qi et al. · Science · 2007 · 1.6K citations

Cardiac Muscle, Cardiac Regeneration, Cardiac Growth +16

The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

Baofeng Yang, Huixian Lin, Jiening Xiao et al. · Nature Medicine · 2007 · 1.1K citations

Cardiac Muscle, Cardiomyopathy, Molecular Physiology +10

miR-133 and miR-30 Regulate Connective Tissue Growth Factor

Rudy F. Duisters, Anke J. Tijsen, Blanche Schroen et al. · Circulation Research · 2008 · 810 citations

Cardiomyopathy, Developmental Biology, Cardiac Reprogramming +15