The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33

IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

Jochen Schmitz, Alexander M. Owyang, Elizabeth R. Oldham et al. · Immunity · 2005 · 3.7K citations · Full text

Life Sciences, Immunology, Cell Signaling +13

IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor <i>in vivo</i>

Virginie Carrière, Lucie Roussel, Nathalie Ortéga et al. · Proceedings of the National Academy of Sciences · 2006 · 949 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Molecular Cloning and Characterization of a Second Subunit of the Interleukin 1 Receptor Complex

Scott Greenfeder, Perla Nunes, Lia Kwee et al. · Journal of Biological Chemistry · 1995 · 640 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Soluble ST2 Blocks Interleukin-33 Signaling in Allergic Airway Inflammation

Hiroko Hayakawa, Morisada Hayakawa, Akihiro Kume et al. · Journal of Biological Chemistry · 2007 · 539 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Cutting Edge: The ST2 Ligand IL-33 Potently Activates and Drives Maturation of Human Mast Cells

Zoulfia Allakhverdi, Dirk E. Smith, Michael R. Comeau et al. · The Journal of Immunology · 2007 · 522 citations · Full text

Life Sciences, Immunology, Allergy +16