Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Ben Langmead, Cole Trapnell, Mihai Pop et al. · Genome biology · 2009 · 23K citations · Full text

Life Sciences, Bioinformatics, High-performance Computing +15

An integrated encyclopedia of DNA elements in the human genome

Nature · 2012 · 19.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Sven Heinz, Christopher Benner, Nathanael J. Spann et al. · Molecular Cell · 2010 · 14.6K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Topological domains in mammalian genomes identified by analysis of chromatin interactions

Jesse R. Dixon, Siddarth Selvaraj, Feng Yue et al. · Nature · 2012 · 7.4K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6.1K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +15