Chemical and Pharmaceutical Bulletin · 1988 · 85 citations · 0 references
PharmacyMicrobiologyBioorganic ChemistryDrug DiscoveryStructure-activity RelationshipsAntibiotic FermentationAntibiotic ProductionAntitumor AntibioticsAntibiotic DiscoveryAntibiotic Mechanisms Of ActionAntimicrobial MetabolitesAntitumor Antibiotic BiosynthesisPhysicochemical Properties
The structures of new antitumor antibiotics, Duocarmycin A, C1 and C2, isolated from the culture broth of Streptomyces sp., have been determined on the basis of chemical and physicochemical evidence.