Does Diabetes Appear in Distinct Phenotypes in Young People? Results of the Diabetes Mellitus Incidence Cohort Registry (DiMelli)

Abstract

The DiMelli study indicated that patients with and without islet autoantibodies differed with respect to metabolic and genetic markers but there was considerable overlap of phenotypes, and autoantibody status could not be predicted by these parameters. Thus, our results suggest that refined diabetes classification may require both immune and metabolic phenotyping.