Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates

Revised methods for the Salmonella mutagenicity test

Dorothy M. Maron, Bruce N. Ames · Mutation Research/Environmental Mutagenesis and Related Subjects · 1983 · 7.4K citations

Pharmacy, Microbiology, Toxicology +7

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

L. F. Chasseaud · Advances in cancer research · 1979 · 1.2K citations

Medicine, Biochemistry, Toxicology +16

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium I. Activation through conjugation with glutathion in vitro

Ulf Rannug, Annica Sundvall, Claes Ramel · Chemico-Biological Interactions · 1978 · 247 citations

Pharmacy, Environmental Sciences, Toxicology +11

Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

Adnan A. Elfarra, Inga Jakobson, M.W. Anders · Biochemical Pharmacology · 1986 · 211 citations

Medicine, Pharmacology, Toxicology +11

The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity

John A. Nash, Laurence J. King, Edward A. Lock et al. · Toxicology and Applied Pharmacology · 1984 · 193 citations · Full text

Pharmacy, Pharmacokinetics, Toxicology +10