Spyridon Vamvakas

Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene

D. Henschler, Spyridon Vamvakas, M. Lammert et al. · Archives of Toxicology · 1995 · 188 citations

Urology, Pathology, Renal Cell Tumors +4

Bacterial β-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene

W. Dekant, Spyridon Vamvakas, Klemens Berthold et al. · Chemico-Biological Interactions · 1986 · 132 citations

Aldehyde Dehydrogenase, Biochemistry, Bacterial β-Lyase +6

Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure.

Gerhard Birner, Spyridon Vamvakas, W. Dekant et al. · Environmental Health Perspectives · 1993 · 108 citations · Full text

Toxicological Mechanism, Oxidative Stress, Urinary Metabolite +22

Bioactivation of tetrachloroethylene. Role of glutathione S-transferase-catalyzed conjugation versus cytochrome P-450-dependent phospholipid alkylation.

W. Dekant, Geert A. Martens, Spyridon Vamvakas et al. · Drug Metabolism and Disposition · 1987 · 82 citations

Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate .beta.-lyase

W. Dekant, Klemens Berthold, Spyridon Vamvakas et al. · Chemical Research in Toxicology · 1988 · 82 citations