Autophagy in the Pathogenesis of Disease

Beth Levine, Guido Kroemer

Cell

Cell AutophagyMitophagyAutoimmune DiseaseAutoantibody ProductionPathogenesis +8

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Yukihiro Kabeya

The EMBO Journal

Cell AutophagyAutophagosome MembranesAutophagyYeastLipophagy +7

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

Tilman Oltersdorf, Steven W. Elmore, Alexander R. Shoemaker, +30

Nature

Tumor BiologyBcl-2 Family ProteinsMedicineSolid TumoursCell Death +7

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

Kurt Degenhardt, Robin Mathew, Brian Beaudoin, +9

Cancer Cell

InflammationCell AutophagyTumor Cell SurvivalApoptosisAutophagy +9

Inhibition of Macroautophagy Triggers Apoptosis

Patricia Boya, Rosa A. González‐Polo, Noëlia Casares, +10

Molecular and Cellular Biology

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

In Hye Lee, Liu Cao, Raúl Mostoslavsky, +6

Proceedings of the National Academy of Sciences

Cell AutophagyMitophagySignal TransductionDevelopmental BiologyCell Regulation +13

Regulation of autophagy by cytoplasmic p53

Ezgi Tasdemir, Maria Chiara Maiuri, Lorenzo Galluzzi, +23

Nature Cell Biology

Cell AutophagyMitophagyCell RegulationCytoplasmic P53Autophagy +5

Functional and physical interaction between Bcl‐XL and a BH3‐like domain in Beclin‐1

Maria Chiara Maiuri, Gaëtane Le Toumelin, Alfredo Criollo, +10

The EMBO Journal

Novel Inhibitors of Cytokine-induced IκBα Phosphorylation and Endothelial Cell Adhesion Molecule Expression Show Anti-inflammatory Effects in Vivo

Jacqueline W. Pierce, Robert Schoenleber, Gary Jesmok, +4

Journal of Biological Chemistry

Programmed Anuclear Cell Death Delimits Platelet Life Span

Kylie D. Mason, Marina R. Carpinelli, Jamie I. Fletcher, +9

Cell

ThrombopoiesisBlood PlateletHematologyBlood CellCell Death +2