Peritoneal Adhesions

Abstract

THE FECTIVENESS of intraperitoneal injection of povidone (Plasdone C) in prevention of reformation of peritoneal adhesions is presented in our preliminary report in 1964.¹The excellent result in reduction of adhesions in two groups of rabbits from 75% to 88% in extent and 57% to 71% in density¹was in favor of further investigation. It was suggested that procedure is practical and has two advantages: simplicity and transient presence of the introduced ascites. The prophylactic result in formation of adhesions which is presented by Choate et al²using dextran in rats, was initiative for investigation of the effect of dextran and comparison with povidone in prevention of reformation of peritoneal adhesions. There are few reports^1,3-5in the literature in favor of our study. The results are indicative that further exploration of the subject is worthwhile and may contribute a solution for an unsolved problem in surgery.