Concepedia

Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells

Stephen Hiscox, L. Morgan, Tim P. Green, Denise Barrow, Julia M.W. Gee, Robert I. Nicholson

Breast Cancer Research and Treatment · 2005 · 273 citations · 40 references

DOI

Concepts

References

40

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Michael D. Schaller, Cheryl A. Borgman, Bradley S. Cobb et al. · Proceedings of the National Academy of Sciences · 1992 · 1.4K citations

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Autophosphorylation of the Focal Adhesion Kinase, ppl25<sup>FAK</sup>, Directs SH2-Dependent Binding of pp60<i><sup>src</sup></i>

Michael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon et al. · Molecular and Cellular Biology · 1994 · 1.1K citations · Full text

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

Michael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon et al. · Molecular and Cellular Biology · 1994 · 868 citations · Full text

, , +17

Src family kinases are required for integrin but not PDGFR signal transduction

Richard A. Klinghoffer, Christoph Sachsenmaier, Jonathan A. Cooper et al. · The EMBO Journal · 1999 · 731 citations · Full text

, , +13

Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

David J. Sieg, Christof R. Hauck, David D. Schlaepfer · Journal of Cell Science · 1999 · 678 citations · Full text

, , +17