Synthesis and Biological Evaluation of Triazolo[4,5-g]quinolines, Imidazo[4,5-g]quinolines and Pyrido[2,3-g]quinoxaline. Part II

Abstract

Synthesis of triazolo[4,5-g]quinolines, imidazo[4,5-g]quinolines and pyrido[2,3-g]quinoxaline has been described.Antimycobacterial, antibacterial and antimycotic activity were also reported.Compounds (14) and (IIb) exhibited an interesting antimycobacterial activity (against M. tuberculosis and M. smegmatis).In continuation of our research program devoted to the discovery of pharmacological activities on new three ring heterocycles, 1-7 we recently described the synthesis of imidazo[4,5-g]-(Ia,b) and triazolo[4,5g]quinolines (Ic,d) and pyrido[2,3-g]quinoxalines (IIa,b) of Figure 1. 8