Oxidant stress-induced loss of IRS-1 and IRS-2 proteins in rat skeletal muscle: Role of p38 MAPK

Reactive oxygen species have a causal role in multiple forms of insulin resistance

Nicholas Houstis, Evan D. Rosen, Eric S. Lander · Nature · 2006 · 2.5K citations

Obesity, Metabolic Syndrome, Insulin Resistance +13

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

Stewart H. Lecker, R. Thomas Jagoe, Alexander D. Gilbert et al. · The FASEB Journal · 2004 · 1.5K citations

Muscle Function, Genetics, Muscle Atrophy Share +21

Activation of Mitogen-activated Protein Kinase by H2O2

Kathryn Z. Guyton, Myriam Gorospe, Qingbo Xu et al. · Journal of Biological Chemistry · 1996 · 1.2K citations · Full text

Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes.

Assaf Rudich, Amir Tirosh, R. Potashnik et al. · Diabetes · 1998 · 474 citations

Metabolic Syndrome, Insulin Signaling, Molecular Physiology +15

Protection Against Oxidative Stress—Induced Insulin Resistance in Rat L6 Muscle Cells by Micromolar Concentrations of α-Lipoic Acid

Betty A. Maddux, Wendy See, John C. Lawrence et al. · Diabetes · 2001 · 407 citations · Full text

Lipid Peroxidation, Insulin Signaling, Alpha-lipoic Acid +18