Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes.

Assaf Rudich, Amir Tirosh, R. Potashnik, +3

Diabetes

Metabolic SyndromeInsulin SignalingMolecular PhysiologyBiochemistryPhysiology +13

Oxidative Stress Disrupts Insulin-induced Cellular Redistribution of Insulin Receptor Substrate-1 and Phosphatidylinositol 3-Kinase in 3T3-L1 Adipocytes

Amir Tirosh, R. Potashnik, Nava Bashan, +1

Journal of Biological Chemistry

Metabolic RemodelingInsulin SignalingOxidative StressMetabolic SyndromeMetabolic Signaling +17

Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes

Assaf Rudich, Nitsan Kozlovsky, R. Potashnik, +1

American Journal of Physiology-Endocrinology and Metabolism

Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes

Assaf Rudich, Amir Tirosh, R. Potashnik, +2

Diabetologia

Metabolic SyndromeInsulin SignalingBiochemistryPhysiologyDiabetes +9

Lipoic acid reduces glycemia and increases muscle GLUT4 content in streptozotocin-diabetic rats

Mogher Khamaisi, R. Potashnik, Amir Tirosh, +5

Metabolism

Metabolic SyndromeMuscle Glut4 ContentBiochemistryPhysiologyGlycobiology +7

Mitogen-Activated Protein Kinases, Inhibitory-κB Kinase, and Insulin Signaling in Human Omental Versus Subcutaneous Adipose Tissue in Obesity

Nava Bashan, Karina Dorfman, Tanya Tarnovscki, +9

Endocrinology

Metabolic DisorderMitogen-activated Protein KinasesAdipokinesInsulin SignalingObesity +19

IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress

R. Potashnik, Asnat Bloch-Damti, Nava Bashan, +1

Diabetologia

Metabolic SyndromeInsulin SignalingBiochemistryDiabetesPhysiology +9

Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress

Asnat Bloch-Damti, R. Potashnik, Philippe Gual, +4

Diabetologia

Insulin ResistanceInsulin SignalingDifferential EffectsBiochemistryPhysiology +8

Intersystem crossing in the charge-transfer quenching of molecular fluorescence

Michael Ottolenghi, C.R. Goldschmidt, R. Potashnik

The Journal of Physical Chemistry

Molecular FluorescenceMolecular SciencesEngineeringChemical AnalysisNatural Sciences +13

Reactive Oxygen Species Activate Glucose Transport in L6 Myotubes11This study was supported by a grant from the Israeli Academy of Sciences.

Nitsan Kozlovsky, Assaf Rudich, R. Potashnik, +1

Free Radical Biology and Medicine

Energy MetabolismMolecular PhysiologyL6 Myotubes11this StudyBiochemistryIsraeli Academy +11