Substantial Proliferation of Human Renal Tubular Epithelial Cell–Reactive CD4+CD28null Memory T Cells, Which Is Resistant to Tacrolimus and Everolimus - Concepedia

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Substantial Proliferation of Human Renal Tubular Epithelial Cell–Reactive CD4+CD28null Memory T Cells, Which Is Resistant to Tacrolimus and Everolimus

20

Citations

36

References

2013

Year

Martijn W.H.J. Demmers, Carla C. Baan, Malou Janssen, Nicolle H. R. Litjens, Jan N.M. IJzermans, Michiel G.H. Betjes, Willem Weimar, Ajda T. Rowshani

Transplantation

Abstract

Our data show substantial proliferation of TEC-reactive CD4CD28 memory T cells, which are resistant to tacrolimus and everolimus. This phenomenon might play an important mechanistic role during cellular rejection under full immunosuppression.

References

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