Comparison of the analgesic effects of various opioid peptides by a newly devised intracisternal injection technique in conscious mice

Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness

Floyd E. Bloom, David J. Segal, Nicholas Ling et al. · Science · 1976 · 812 citations

Medicine, Neuroscience, Pharmacology +17

Evidence for analgesic activity of enkephalin in the mouse

Heinz H. Büscher, Ronald C. Hill, D. Römer et al. · Nature · 1976 · 252 citations

Medicine, Neuroscience, Pharmacology +12

Analgesia induced by microinjection of morphine into, and electrical stimulation of, the nucleus reticularis paragigantocellularis of rat medulla oblongata

A Akaike, Takashi Shibata, Masamichi Satoh et al. · Neuropharmacology · 1978 · 186 citations

Life Sciences, Neuroscience, Pharmacology +16

A MODIFICATION OF HAFFNER’S METHOD FOR TESTING ANALGESICS

Hiroshi Takagi, Toshiya Inukai, Mototaka Nakama · The Japanese Journal of Pharmacology · 1966 · 173 citations · Full text

Nursing, Pharmacology, Pain Management +12

Comparative study on analgesic effect of Met5-enkephalin and related lipotropin fragments

L. Gráf, József I. Székely, András Z. Rónai et al. · Nature · 1976 · 147 citations

Medicine, Pharmacology, Pharmacotherapy +13