PTEN/PI3K/mTOR/B7-H1 signaling pathway regulates cell progression and immuno-resistance in pancreatic cancer. - Concepedia

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PTEN/PI3K/mTOR/B7-H1 signaling pathway regulates cell progression and immuno-resistance in pancreatic cancer.

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References

2013

Year

Yingfei Zhang, Jianlong Zhang, Kang Xu, Zhiyu Xiao, Jian Sun, Junyao Xu, Jie Wang, Qibing Tang

Abstract

Our results demonstrated deletion of PTEN in pancreatic cancer cells induced the expression of B7-H1, which contributed to immune suppression and increased cancer progression and invasion.