Tachykinin antagonists have potent local anaesthetic actions

Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation

Fred Lembeck, Peter Holzer · Naunyn-Schmiedeberg s Archives of Pharmacology · 1979 · 1.2K citations

Medicine, Pharmacology, Physiology +14

A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig

Jan M. Lundberg, Alois Saria, Ernst Brodin et al. · Proceedings of the National Academy of Sciences · 1983 · 436 citations · Full text

Medicine, Pharmacology, Clinical Pharmacology +13

Tachykinin antagonists

Expert Opinion on Therapeutic Patents · 1994 · 365 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Release of substance P-like immunoreactivity from isolated spinal cord of newborn rat

Masanori Otsuka, Shiro Konishi · Nature · 1976 · 287 citations

Life Sciences, Neurobiology, Neuroscience +10

A specific substance P antagonist blocks smooth muscle contractions induced by non-cholinergic, non-adrenergic nerve stimulation

S. Leander, R. Håkanson, Sune Rosell et al. · Nature · 1981 · 270 citations

Medicine, Pharmacology, Neuropharmacology +4