Synthesis and biological evaluation of novel sinomenine derivatives as anti-inflammatory agents

Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

Carl Nathan · Journal of Clinical Investigation · 1987 · 806 citations · Full text

Life Sciences, Cell Biology, Immunology +10

From Models to Molecules:  Opioid Receptor Dimers, Bivalent Ligands, and Selective Opioid Receptor Probes

Philip S. Portoghese · Journal of Medicinal Chemistry · 2001 · 188 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Synthesis of Alkyl Aryl Ethers by Catalytic Williamson Ether Synthesis with Weak Alkylation Agents

Edgar Fuhrmann, Jörg Talbiersky · Organic Process Research & Development · 2005 · 159 citations

Natural Sciences, Chemistry, Catalysis +9

Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum.

Hidemasa Yamasaki · PubMed · 1976 · 139 citations · Full text

Medicine, Botany, Pharmacology +14

Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats

Yong Wang, Yongfei Fang, Wenhua Huang et al. · Journal of Ethnopharmacology · 2005 · 125 citations

Medicine, Immunology, Pharmacology +14