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2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character

Maƚgorzata Dukat, Katie Alix, Jessica Worsham, Shailesh Khatri, Marvin K. Schulte

Bioorganic & Medicinal Chemistry Letters · 2013 · 39 citations · 19 references

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19

Lead- and drug-like compounds: the rule-of-five revolution

Christopher A. Lipinski · Drug Discovery Today Technologies · 2004 · 6.1K citations

, , +14

Depression: a new animal model sensitive to antidepressant treatments

Roger D. Porsolt, Manuel Pichon, M Jalfre · Nature · 1977 · 4.4K citations

, , +12

The tail suspension test: A new method for screening antidepressants in mice

Lucien Stéru, R Chermat, Bernard Thierry et al. · Psychopharmacology · 1985 · 3.5K citations

, , +11

Hydrophobicity and Central Nervous System Agents: On the Principle of Minimal Hydrophobicity in Drug Design

Corwin Hansch, J.P. Björkroth, Albert J. Leo · Journal of Pharmaceutical Sciences · 1987 · 435 citations

, , +14

Effect of Selective Serotonin Reuptake Inhibitors on the Risk of Fracture

J. Brent Richards · Archives of Internal Medicine · 2007 · 387 citations

, , +16